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Clinical observation on therapeutic effect of low-molecule heparin integrated with Ginkgo-dipyidamolum injection on unstable angina pectoris

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Author:
LUO Chi-quan(Department of Internal Medcine.Zhaoqing No. 1 People's Hospital, Guangdong Province, Zhaoqing 526020, China)
HUANG Shi-zhou(Department of Internal Medcine.Zhaoqing No. 1 People's Hospital, Guangdong Province, Zhaoqing 526020, China)
Journal Title:
China Medicine
Issue:
Volume 06, Issue 10, 2011
DOI:
10.3760/cma.j.issn.1673-4777.2011.10.004
Key Word:
Angina pectoris, unstable;Low-molecule heparin;Ginkgo dipyidamolum

Abstract: Objective To study the therapeutic effect of low-molecule heparin (LMWH) and Ginkgo-dipyidamolum injection for unstable angina (UA). Methods One hundred and seventy-five cases with UA were chosen from March 2006 to March 2010, completely randomly divided into treatment group (58 cases) and control group Ⅰ (52 cases) and control group Ⅱ (65 cases). On the basis of routine therapy, control and treatment groups for UA patients were established, and for experimental group, 58 patients were treated with both LMWH and Ginkgo-dipyidamolum injection. Results Statistically,compared with control group, the treatment of experimental group is more effective on aspects as follows: easing clinical symptoms, allaying myocardial ischemia diagnosed by electrocardiogram, and preventing composite of non-fatal stroke, myocardial infarction and cardiovascular death[82.76% (48/58 ) vs 65.38% (34/52) ,63.08% (41/65) ;77.59% (45/58) vs 55.77% (29/52) ,53.85% (35/65) ;18.97% (11/58)vs36.54%(19/52),35.38%(23/65),P<0. 05,P<0.01]. Conclusion LMWH and Ginkgo-dipyidamolum injection are more effective than that of either LMWH or Ginkgo-dipyidamolum injection on abirritating myocardial blooding and relieving clinical symptom.

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