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The morning peak of acute myocardial infarction' s onset and its risk factors

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Author:
No author available
Journal Title:
CHINA MEDICINE
Issue:
8
DOI:
10.3760/cma.j.issn.1673-4777.2011.08.001
Key Word:
心肌梗死;发病时间;清晨高峰;危险因素;Myocardial infarction;Time of onset;Morning peak;Risk factors

Abstract: Objective To investigate the morning peak of onset time in patients with acute myocardial infarction(AMI) and its risk factors. Methods A retrospective analysis of patients(n = 874) diagnosed with AMI between October 2002 and September 2006 in Peking University people's hospital was carried out. We calculated the number and the percentage of AMI cases and found out the morning peak time of AMI's onset. The clinical factors in relation to the peak time of AMI's onset were analyzed using multivariate unconditional Logistic regression. Results There was a circadian rhythm of AMI with a peak incidence during 6:01-9:00 (P<0. 05, compared with other times). Logistic regression analysis showed that the risk factors of the morning peak of AMI's onset included men (0R= 1.74, 95% CI: 1.11-2.73, P<0.05), the history of hypertension (OR =1.71, 95% CI:1. 17-2.51, P< 0.01) and the preinfarction angina(OR = 1.61, 95%CI:1.08-2. 38, P<0.05). Conclusions AMI is more likely to happen in the morning hours. Men, hypertension and the preinfarction angina are the independent risk factors associated with AMI's onset.

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