The significance of classification of chronic nonbacterial prostatitis by detecting interleukin-8 and tumor necrosis factor-α in EPS
- Author:
- No author available
- Journal Title:
- CHINA MEDICINE
- Issue:
- 11
- DOI:
- 10.3760/cma.j.issn.1673-4777.2010.11.027
- Key Word:
- 前列腺炎;白细胞介素8;肿瘤坏死因子α;Prostatitis;Interleukin-8;Tumor necrosis factor-α
Abstract： Objective To investigate the significance of interleukin-8(IL-8)and(TNF-α)in expressed prostatic secretion(EPS)for diagnosis and classification of prostatitis Ⅲ [chronic nonbacterial prostatitis/chronic pelvic pain syndrome(CPPS)]. Methods IL-8 and TNF-α levels in EPS were evaluated by ELISA in 60 men:controls(n=20),CPPS ⅢA(n =34),CPPS ⅢB(n =26).And the difference was analyzed among CPPS Ⅲ A and CPPS Ⅲ B and controls. Results The levels of IL-8 and TNF-α in EPS of patients with chronic nonbacterial prostatitis group Ⅲ A were significantly different compared with group ⅢB and control group(P ＜0.01);IL-8 and TNF-α levels in group Ⅲ B was higher than the control group(P ＜ 0.05). Conclusion The detection of IL-8 and TNF-α levels in patients with prostatitis may contribute to diagnosis and classification of prostatitis Ⅲ.
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