Abstract: Objective To investigate the diagnosis and treatment of pseudomyxoma peritonei (PMP).Methods Retrospective study was made for 32 cases of PIMP.Results Main clinical presentations included abdominal pain, distention, mass and wasting of whole body.Uhrasonography showed heterogeneous ascites in 10 cases.Level of CEA elevated in 26 cases.All patients were performed an operation.Primary tumor was proved pathologically: 20 cases of appendiceal mutinous carcinoma, 2 eases of ovarian mutinous carcinoma and 1 case of descending colon mutinous carcinoma.Surgical procedure included resection of primary tumour, omenteetomy, removal of mucinous ascites and combined resection of organs involved.Postoperative adjuvant chemotherapy and/or radiotherapy was added.Conclusions PMP is a rare condition and difficult to diagnosis.Imaging examination and CEA may help make a diagnosis.Treatment of PMP is mainly surgical operation and adjuvant therapy.