You Position: Home > Paper

The predictive value of glycosylated hemoglobin level in patients with acute myocardial infarction

( views:313, downloads:136 )
Author:
No author available
Journal Title:
CHINA MEDICINE
Issue:
5
DOI:
10.3760/cma.j.issn.1673-4777.2010.05.001
Key Word:
急性心肌梗死;糖化血红蛋白;预后;Acute myocardial infarction;Glycosylated hemoglobin;Prognosis

Abstract: Objective To evaluate the glycosylated hemoglobin (HbA1c) level in patients with acute myocardial infarction.Methods The data of 474 in-hospital patients with ST-elevation myocardial infarction were collected from database of Beijing Anzhen Hospital from January to December 2008.The patients were divided into two groups according to the level of HbA1c:HbAlc≥6.5% group and control group (HbAlc<6.5%).The prognosis of two groups were observed.Results Age,smoke,ischemic time,cases of coronary angiography,successful reperfusion rate,in-hospital drug us were no significant different between two groups(P>0.05).Compared with the control group,history of hypertension(P=0.008) and diabetes (P=0.000),blood glucose (P=0.000),triplevessel disease (P=0.031),male (P=0.006),LVEF (P=0.023) and single-vessel disease (P=0.040) were significantly different in HbA1c≥6.5% group.In HbA1c≥6.5% group,there was higher incidence of heart failure (P=0.041),in-hospital mortality (P=0.033),cardiogenic shock (P=0.038).Logistic analysis showed that HbA1c≥6.5% were independent factors of in-hospital mortality(OR=0.932,95% CI:0.311-1.124,P=0.044) and the rate of heart failure (OR=1.467,95% CI:0.473-3.149,P=0.047).Conclusions The high level of HbA1c is a powerful predictor of in-hospital mortality and incidence of heart failure in patients with acute myocardial infarction.The prognosis of AMI can be improved by the control of blood sugar.

WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn