Effect of trimetazidine on unstable angina
- Author:
- No author available
- Journal Title:
- CHINA MEDICINE
- Issue:
- z1
- DOI:
- 10.3760/cma.j.issn.1673-4777.2009.13.001
- Key Word:
- 不稳定型心绞痛;曲美他嗪;临床疗效;Unstable angina;Trimetazidine;Clincal outcomes
Abstract： Objective To explore the effect of trimetazidine in patients with unstable angina(UA).Methods One hundred and sixteen UA cases were randomly divided into control group (n=60)and trimetazidine group(n=56). All patients were treated by routine therapy such as isosorbide dinitrate,anticoagulant, β-ntblock receptor agent,calcium antagonists,blood lipid-lowering,reducing hypertension and antiplatelet. trimetazidine 20 mg after each of the three meals was taken in trimetazidine group,the total period of treatment was 4 weeks.Results Terimezidiue was effective in 56 cases and LVEF increased.No severe side effects were found during the treatment related to the trimezidine. Conclusion For patients with UA, trimetazidine is effective and improves the heart function.The drug is safe and well torelated by patients.
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