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Treatment of avascular necrosis of femoral head by cytotherapy based on enrichment technique of bone marrow stem cells

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Author:
LI Ya-fei(Department of Orthopedics,Beijing Health Palace Hospital,Beijing 100054,China)
ZOU Yu-wei(Department of Orthopedics,Beijing Health Palace Hospital,Beijing 100054,China)
LI Gen-bao(Department of Orthopedics,Beijing Health Palace Hospital,Beijing 100054,China)
CHEN Yan(Department of Orthopedics,Beijing Health Palace Hospital,Beijing 100054,China)
YAO Jian-hua()
MA Wen-hui()
SHI Shu-shan()
CHEN Xi-shun()
GUO Ying()
QI Li-hai()
ZHANG Lu-song()
PAN De-jin(Department of Orthopedics,Beijing Health Palace Hospital,Beijing 100054,China)
WANG Qi()
WANG Rui-min()
SUN Guo-shao()
ZHANG Jian-zheng()
CHANG Hong-xing()
GUO Yong-zhi()
FANG Chong-rui(Department of Orthopedics,Beijing Health Palace Hospital,Beijing 100054,China)
CAO Hong-guo()
LI Dong-chao(Department of Orthopedics,Beijing Health Palace Hospital,Beijing 100054,China)
HU Zhen-zhong(Department of Orthopedics,Beijing Health Palace Hospital,Beijing 100054,China)
Journal Title:
CHINA MEDICINE
Issue:
Volume 4, Issue 10, 2009
DOI:
10.3760/cma.j.issn.1673-4777.2009.10.001
Key Word:
Femur head necrosis;Bone grafting;Bone marrow stem cells;Bone morphogenetic protein;Tissue engineering

Abstract: cal support to prevent the necrotic femoral head from progressing and collapsing,meanwhile enriched BMSCs promote new bone formation.The method can be used as an alternative for the treatment of osteonecrosis of femoral head at stage Ⅰ and Ⅱ.

  • [1]Garino JP,Steinberg ME.Total hip arthmplasty in patients with avascular necrosis of the femoral head:a 2-to 10-year follow-up[J].Clin Orthop Pelat Res,1997,(334):108-115.
  • [2]王岩,朱盛修,赵德伟.带旋髂深血管蒂髂骨骨膜移植治疗股骨头缺血性坏死及疗效评价[J].中华骨科杂志,1995,15(9):567-569.
  • [3]Wang Y,Zhu S,Zhao D.Vascularized iliac periosteal txansfor for the treatment of avastular necrosis of the femoral head and a new evaluation grading system[J].Chin Med J(Engl),1996,109(6):441-445.
  • [4]Salvati EA,Cornell CN.Long-term follow-up of total hip replacement in patients with avascular necrosis[J].Instr Course Lect,1988,37:67-73.
  • [5]Brown TD,Pedersen DR,BaKer KJ,et al.Mechanical comsequences of core drilling and bone-grafting on osteonecrosis of the femoral head[J].J Bone Joint Surg Am,1993,75(9):1358-1367.
  • [6]Kim YM,Lee SH,Lee FY,et al.Morphologic and biomechanical study of avaseular necrosis of the femoral head[J].Orthopedics,1991,14(10):1111-1116.
  • [7]常红星,李亚非,时述山,等.兔自体骨髓基质细胞经皮移植修复骨缺损的实验观察[J].中国矫形外科杂志,2004,12(12):925-926.
  • [8]Mont MA,Jones LC,Einhorm TA,et al.Osteonecrosis of the femoral head:Potential treatment with growth and differentiation factors[J].Clin Orthop Relat Res,1998,(335 suppl):S314-S335.
  • [9]薛元锁.时述山,李哑非,等.激素性股骨头坏死病程中骨形态发生蛋白-2的改变及其意义[J].中华实验外科杂志,2000,17(5):455-456.
  • [10]马文辉,时述山,李亚非.神经肽对人成骨细胞生物学影响机理的研究[J].中国矫形外科杂志.2001,8(11):1091-1095.
  • [11]李亚非,姚建华,马文辉,等.神经肽和人骨形态发生蛋8-2对体骨-成骨细胞复合物成骨能力的观察[J].中国学术期刊文摘,2000,6(6):625-627.
  • [12]李亚非,时述山,李青,等.大段异体骨关节移植后长期转归的观察[J].中华外科杂志.1998,36(3):169-171.
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