Abstract： Objective To report our experience of rescuing acute myocanfial infarction on spot. Methods Clinical data of 66 patients with AMI salvage at scene by emergency rescue centre of our hospital from March 2002 to January 2005 was reviewed. Results There were 26 patients with inferior myocardial infarction and 40 patients with the other parts myocardial infarction. Eight of 12 patients (66.7%) received thmmholytic therapy at scene. Five patients got the reperfusion arrhythmias RA (41.6%, 2 patients with premature ventricualr contraction, 1 patients with accelerated ventricular tachycardia, 2 patients with premature atrial contraction). There were 51 cases with sequela, including 13 cases with widespread anterior wall necrotic Q wave, 18 cases with inferior wall necrotic Q wave, 10 cases with antero-septal wall necrotic Q wave, 6 cases with atrial fibrillation and 4 cases with cardia failure. During 30 days of thrombolytic therapy, there was no alimentary tract hemorrhage, cerebral hemorrhage and widespread skin congestion. Conclusion Early diagnosis of AMI should be primarily made according to clinical manifestation and ECG. Early access to treatment procedures and rehabilitation myocardial peffusion is the key to success-ful resuscitation.