Abstract: Objective To observe the therapeutic effect of psychotherapy in sexual dysfunction caused by chronic prostates. Methods Two hundred and fifty three patients of chronic prostatitis with sexual dysfunction, were randomly divided into experimental group (112 cases) and control group( 141 cases). Experimental group received general therapy and psychotherapy, control group only had general therapy. Two scoring systems, Chinese index of sexual function for premature ejaculation ( CIPE-5 ) and the International Index of Erectile Function ( IIEF-5 ) were used in this study. Results In experimental group, 75.5% of premature ejaculation was improved, which was significantly higher than control group( 59.3% ). Conclusion psychotherapy combined with general therapy showed a better outcome in treatment of sexual dysfunction caused by chronic prostates.