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Clinical analysis of rapamycin drug-eluting stent thrombosis after Primary percutaneous coronary intervention

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Author:
AI Hui(Emergency Center Institute of Heart, Lung and Blood Vessel Diseases & Beijing Anzhen Hospital of the Capital University of Medical Sciences Beijing 100029, China)
ZHU Xiao-ling(Emergency Center Institute of Heart, Lung and Blood Vessel Diseases & Beijing Anzhen Hospital of the Capital University of Medical Sciences Beijing 100029, China)
YAN Hong-bing(Emergency Center Institute of Heart, Lung and Blood Vessel Diseases & Beijing Anzhen Hospital of the Capital University of Medical Sciences Beijing 100029, China)
GAO Hai(Emergency Center Institute of Heart, Lung and Blood Vessel Diseases & Beijing Anzhen Hospital of the Capital University of Medical Sciences Beijing 100029, China)
LI Nan(Emergency Center Institute of Heart, Lung and Blood Vessel Diseases & Beijing Anzhen Hospital of the Capital University of Medical Sciences Beijing 100029, China)
WANG Jiang(Emergency Center Institute of Heart, Lung and Blood Vessel Diseases & Beijing Anzhen Hospital of the Capital University of Medical Sciences Beijing 100029, China)
ZHANG Xiao-jiang(Emergency Center Institute of Heart, Lung and Blood Vessel Diseases & Beijing Anzhen Hospital of the Capital University of Medical Sciences Beijing 100029, China)
LI Shi-ying(Emergency Center Institute of Heart, Lung and Blood Vessel Diseases & Beijing Anzhen Hospital of the Capital University of Medical Sciences Beijing 100029, China)
Journal Title:
CHINA MEDICINE
Issue:
Volume 3, Issue 06, 2008
DOI:
Key Word:
ST-segment elevation mycocavdial infarction; Percutaneous coronary intervention; Drugeluting stent; Stent thrombosis

Abstract: Objective To observe Rapamycin drug-eluting stent thrombosis after primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI). Methods Primary PCI with implantation of rapamycin drug-eluting stent was performed in 521 patients with STEMI. Among them, 12 cases suffering from stent thrombosis after PCI were observed. Results The incidence of stent thrombosis was 2.5% ( 13/521), the death rate of the 12 cases in 6 months was 41.7% (5/12). Meanwhile enlarged left ventricular end diastolic diameter and reduced left ventricular ejection fraction occurred in 7 survival patients within 6 months.Conclusion Rapamycin drug-eluting stent thrombosis was a clinical incident with multiple risk factors and related to high mortality and poor prognosis.

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