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Analysis of correlation between lung cancer treatment and fungal infection

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Author:
No author available
Journal Title:
CHINA MEDICINE
Issue:
4
DOI:
10.3760/cma.j.issn.1673-4777.2008.04.005
Key Word:
肺癌;真菌感染;Lung cancer;Fungal infection

Abstract: Objective To analyze the correlation between lung cancer treatment and fungal infection.Methods Altogether 2083 patients with lung cancer were enrolled in this retrospective study.The patients wereclassified by methods of therapy,including operative group and non-operative group,antibiotic group and non-antibiotic group,radiotherapy group,chemotherapy group,radiochemotherapy group,hormone group and cathetertherapy group.Results Out of the 2083 patients,14.16%were diagnosed of airway fungal infection.The differenceof infection rate was not significant between operation group and non-operation group(P>0.05).Among the operationgroup,the Ⅳ phase cancer patients had significantly higher infection rate than Ⅲ phase patients(P<0.01).Thepatients who had received chemotherapy,or combination of chemotherapy and radiotherapy had a higher infection ratethan those who received radiotherapy only(P<0.05).Those who received antimierobial treatment had a higherinfection rate than those who received antimicrobial propbylaxis(P<0.05).Specifically,the more antimicrobials Wasused,the more significant the difference was(P<0.01).Conclusion The incidence of fungal infection in lungcancer patients is related to the use of antibiotics,chemotherapy,operation,hormone therapy and catheter therapy.

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