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Effect of serum pregnancy-associated plasma-A level in patients with acute coronary syndrome treated with TATIN
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- Author:
- No author available
- Journal Title:
- CHINA MEDICINE
- Issue:
- 9
- DOI:
- 10.3760/cma.j.issn.1673-4777.2007.09.005
- Key Word:
- 急性冠状动脉综合征;妊娠相关性蛋白-A;易损斑块
Abstract： 目的 探讨应用他汀类药物后急性冠状动脉综合征(ACS)患者妊娠相关性血浆蛋白-A(PAPP-A)水平的变化.方法 应用双抗夹心酶联免疫吸附法(ELISA)分别测定40例ACS应用他汀类药物前后、20例稳定型心绞痛(SA)及20例非冠心病患者血清PAPP-A水平.结果 ACS患者血清PAPP-A浓度均明显高于SA组和非冠心病组患者,应用他汀类药物后ACS患者血清PAPP-A水平降低(均P＜0.01).结论 PAPP-A浓度在ACS患者血中明显升高,为ACS易损斑块新的血清标志物.
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