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Relationship Between plasma natriuretic peptide and right ventricular function in the patients with chronic heart failure.
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- Author:
- No author available
- Journal Title:
- CHINA MEDICINE
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.1673-4777.2006.07.002
- Key Word:
- 心力衰竭;脑钠肽;右心功能
Abstract： 目的探讨慢性心力衰竭患者脑钠肽(BNP)升高与右心室功能之间的关系.方法以ELISA法和PHILIPS 5500型彩色多普勒超声心动仪,对39例扩张型心肌病(DCM)和40例高血压性心脏病(高心病)患者行血浆BNP和心功能检测.结果在心功能相同状态下,DCM组血浆中BNP明显高于高心病组,两者左心房舒张末期直径(LAEDD)、左心室舒张末期直径(LVEDD)无明显差异,但右心室舒张末期直径(RVEDD)DCM组与高心病组有明显差别(P＜0.05).DCM组中血浆BNP水平与RVEDD呈正相关(r=0.803,P＜0.01).结论在慢性心功能不全的患者,血浆中BNP除与左心功能、LVEDD相关外,与RVEDD也有明显的正相关性.
- [1]Keiko Maeda,Takayoshi Tsutamoto,Atsuyuki Wada,etc.Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction[J].1998,135(5).
- [2]Kazanegra R,Hlavin P,Amirnovin R,etc.Utility of B-type natriuretic peptide in the diagnosis of congestive heart failure in an urgent-care setting.[J].2001,37(2).
- [3]T, Sudoh,K, Kangawa,N, Minamino,etc.A new natriuretic peptide in porcine brain.[J].1988,332.
- [4]Nakagawa O,Nishino K,Kishimoto I,etc.Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.[J].1995,96(3).