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Levels and significance of serum soluble cell adhesion molecules in acute coronary syndrome

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Author:
No author available
Journal Title:
CHINA MEDICINE
Issue:
5
DOI:
10.3760/cma.j.issn.1673-4777.2006.05.003
Key Word:
急性冠状动脉综合征;细胞间粘附分子-1;血管细胞粘附分子-1

Abstract: 目的探讨血清细胞间粘附分子(CAMs)在急性冠状动脉综合征(ACS)发生发展过程中的作用.方法用双抗体酶联免疫吸附法测定40例ACS患者及40例健康体检者血清可溶性细胞间粘附分子-1(sICAM-1)、血管细胞粘附分子-1(sVCAM-1)、E-选择素(sE-S)的浓度.结果ACS组血清sICAM-1、sVCAM-1及sE-S的浓度分别为(371.78±66.78)μgL、(644.91±169.73)μg/L及(46.14±10.14)μg/L,明显高于正常对照组的(236.45±47.55)μg/L、(342.16±84.16)μg/L及(31.30±5.40)μg/L(P<0.05或P<0.01).结论CAMs参与了ACS的发病过程.

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