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Efficacy and safety of salvage therapy in lamivudine resistant children with chronic hepatitis B
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1674-2397.2010.04.015
- Key Word:
- 肝炎,乙型,慢性;拉米夫定;阿德福韦酯;挽救性治疗;儿童;Chronic hepatitis B;Lamivudine;Adefovir dipivoxil;Salvage therapy;Child
Abstract： @@ 拉米夫定是治疗慢性乙型肝炎的主要药物之一,但存在治疗见效停药后肝炎再次复发的问题.拉米夫定耐药后联用阿德福韦酯治疗称为"挽救性治疗",这种方案已在成人中应用,临床上证实安全、有效[1-2],但在儿童人群中研究较少.本文通过观察30例阿德福韦酯联合拉米夫定挽救性治疗拉米夫定耐药后肝炎复发的慢性乙型肝炎患儿,探索该方案在儿童中应用的疗效与安全性.
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