Clinical significance of MPO and HIF-1α levels in serum and ascites of patients with hepatopulmonary syndrome

( views:143, downloads:0 )
Author:
WANG Yan-feng(Department of Gastroenterology,Heilongjiang Provincial Hospital,Harbin 150036,China)
MA Hong()
ZHANG Yan-xia(Department of Gastroenterology,Heilongjiang Provincial Hospital,Harbin 150036,China)
ZHAO Xin(Department of Gastroenterology,Heilongjiang Provincial Hospital,Harbin 150036,China)
WANG Yan-yin(Department of Gastroenterology,Heilongjiang Provincial Hospital,Harbin 150036,China)
Journal Title:
CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
Issue:
Volume 3, Issue 02, 2010
DOI:
10.3760/cma.j.issn.1674-2397.2010.02.012
Key Word:
Hepatopulmonary syndrome;Myeloperoxidase;Hypoxia-inducible factor-1α

Abstract:

  • [1]Schenk P,Fuhrmann V,Madl C,et al.Hepatopulmonary syndrome:prevalence and predictive value of various cut offs for arterial oxygenation and their clinical consequences.Gut,2002,51(6):853-859.
  • [2]Aller R,Moreira V,Boixeda D,et al.Diagnosis of hepatopulmonary syndrome with contrast transthoracic echocardiography and histological confirmation.Liver,1998,18(4):285-287.
  • [3]李夏,韩德五,赵龙凤.甘氨酸对非乙醇性脂肪性肝病大鼠肝组织PPARα表达的影响.中国病理生理杂志,2006,22(9):1829-1832.
  • [4]赵龙凤,黄彤,李红,等.甘氨酸对慢性乙型肝炎临床疗效的影响.山西医科大学学报,2004,35(3):270-272.
  • [5]陈玺华,王锋,韩德五,等.甘氨酸抗内毒素性休克和肝损伤的作用及其机制.中华实验外科杂志,2003,20(5):415-417.
  • [6]刘近春,韩德五,许瑞玲,等.甘氨酸在肝硬化发生发展过程中对肝组织CD14基因及蛋白表达的影响.中华肝脏病杂志,2002,10(3):181-184.
  • [7]Bruck R,Wardi J,Aeed H,et al.Glycine modulates cytokine secretion,inhibits hepatic damage and improves survival in a model of endotoxemia in mice.Liver Int,2003,23(4):276-282.
  • [8]叶任高,陆再英.内科学.6版.北京:人民卫生出版社,2004:440-449.
  • [9]Klaes R,Friedrich T,Spitkovsky D,et al.Overexpression of p16(INK4A)as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri.Int J Cancer,2001,92(2):276-284.
  • [10]Krowka MJ,Cortese DA.Hepatopulmonary syndrome:current concepts in diagnostic and therapeutic considerations.Chest,1994,105(5):1528-1537.
  • [11]Rodríguez-Roisin R,Krowka MJ.Hepatopulmonary syndrome-a liver-induced lung vascular disorder.N Engl J Med,2008,358(22):2378-2387.
  • [12]Narumiya S,Ishizaki T,Watanabe N.Rho effectors and reorganization of actin cytoskeleton.FEBS Lett,1997,410(1):68-72.
  • [13]García-Casasola G,Nacher J,Fernández C,et al.Severe polycythemia as the first clinical presentation of hepatopulmonary syndrome.J Clin Gastroenterol,2003,37(1):89-91.
  • [14]Fanning AS,Mitic LL,Anderson JM.Transmembrane proteins in the tight junction barrier.J Am Soc Nephrol,1999,10(6):1337-1345.
  • [15]Brain JD,Molina RM,DeCamp MM,et al.Pulmonary intravascular macrophages:their contribution to the mononuclear phagocyte system in 13 species.Am J Physiol,1999,276(1 Pt1):L146-154.
  • [16]Colgan SP,Dzus AL,Purkos CA.Epithelial exposure to hypoxia modulates neutrophil transepithelial migration.J Exp Med,1996,184(3):1003-1015.
  • [17]Bailey MT,Engler H,Sheridan JF.Stress induces the translocation of cutaneous and gastrointestinal microflora to secondary lymphoid organs of C57BL/6 mice.J Neuroimmunol,2006,171(1-2):29-37.
  • [18]Cutrn JC,Perrelli MG,Cavalieri B,et al.Microvascular dysfunction induced by reperfusion injury and protective effect of ischemic preconditioning.Free Radic Biol Med,2002,33(9):1200-1208.
  • [19]Fondevila C,Busuttil RW,Kupiec-Weglinski JW.Hepatic ischemia/reperfusion injury-a fresh look.Exp Mol Pathol,2003,74(2):86-93.
  • [20]Zhang C,Reiter C,Eiserieh JP,et al.L-Arginine chlorination products inhibit endothelial nitric oxide production.J Biol Chem,2001,276(29):27159-27165.
  • [21]Auchère F,Capeillère-Blandin C.NADPH as a co-substrate for studies of the chlorinating activity of myeloperoxidase.Biochem J,1999,343(pt3):603-613.
  • [22]Kallio PJ,Wilson WJ,O'Brien S,et al.Regulation of the hypoxia inducible transcription factor 1 alpha by the ubiquitin proteasome pathway.J Biol Chem,1999,274(10):6519-6525.
  • [23]Semenza GL.HIF-1,O(2),and the 3 PHDs:how animal cells signal hypoxia to the nucleus.Cell,2001,107(1):1-3.
  • [24]任学群,孟继明,傅侃达.P53及缺氧诱导因子-1α表达与结直肠癌血管生成的关系.中国医学工程,2004,12(4):31-35.
  • [25]Semenza GL.Expression of hypoxia inducible factor-1α echanisms and consequences.Biochem Pharmacology,2000,59(1):47-53.
  • [26]宋虎平,惠延年,王丽丽,等.缺氧诱导因子-1α在早期糖尿病大鼠角膜上皮细胞中的表达.国际眼科杂志,2006,6(2):352-356.
  • [27]Huang LE,Arany Z,Livingston DM,et al.Activation of hypoxiainducible transcription factor depends primarily upon redoxsensitive stabilization of its alpha subunit.J Biol Chem,1996,271(50):32253-32259.
  • [28]Lai YL,Law TC.Chronic hypoxia-and monocrotaline-induced elevation of hypoxia inducible factor-1 alpha levels and pulmonary hypertension.J Biomed Sci,2004,11(3):315-321.
  • [29]Wu XZ,Xie GR,Chen D.Hypoxia and hepatocellular carcinoma:the therapeutic target for hepatocellular carcinoma.J Gastroenterol Hepatol,2007,22(8):1178-1182.
  • [30]Huang LE,Willmore WG,Gu J,et al.Inhibition of hypoxiainducible factor 1 activation by carbon monoxide and nitric oxide.Implications for oxygen sensing and signaling.J Biol Chem,1999,274(13):9038-9044.
  • [31]Alizadeh AH,Fatemi SR,Mirzaee V,et al.Clinical features of hepatopulmonary syndrome in cirrhotic patients.World J Gastroenterol,2006,12(12):1954-1956.
  • [32]马宏,赵欣,王燕颖,等.肝肺综合征患者缺氧诱导因子-1α和诱导型一氧化氮合酶水平与门脉血流动力学的研究.中国基层医药,2009,9(16):17-20.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn