Investigation of nosocomial infection of 6395 hospitalized neonates

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Author:
WU Xiang-lan(Department of Neonate Care, Maternal and Child Health Care Institute of Bao'an District,Shenzhen 518133, China)
CHEN Chao-hong(Department of Neonate Care, Maternal and Child Health Care Institute of Bao'an District,Shenzhen 518133, China)
LI Yue-feng(Department of Neonate Care, Maternal and Child Health Care Institute of Bao'an District,Shenzhen 518133, China)
Journal Title:
CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
Issue:
Volume 1, Issue 05, 2008
DOI:
Key Word:
Neonate;Nosocomial infection;Risk factor;Preventive measure

Abstract: Objective To identify risk factors, incidence and trends of nosocomial infections in the neonate ward. Methods Total 6395 hospitalized neonates were sub-grouped by state of maturity, attending to neonate intensive care unit (NICU), length of stay, underlying diseases, use of antibacterial agents and mechanical ventilation. Clinical data were retrospectively analyzed in each subgroup. Results Among 6395 hospitalized neonates, 168 (2.63%) had nosocomial infections, and the incidence rates were of statistical difference among groups (P<0.01), Lower respiratory tract was the most frequent infection site accounting for 80.9% of all infections. 61.3% eases were caused by gram negative bacteria, in which 72.06% were enterobacteriaceae. Conclusions To prevent nosecomial infection among neonates the following measures should taken: improve care for NICU and premature babies, reduce length of stay, avoid invasive procedures, isolate infected neonates and use antibacterial agents rationally.

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