Abstract： Objective To create an integrated digital maxillodental model and to apply it in computer aided design (CAD) of individnalized lingual brackets in order to align both crowns and roots without fenestration and dehiscence. Methods Cone-beam computerized tomography (CBCT)-based maxillodental model and laser-scanned dental model were integrated by auto registration in 10 patients with malocclusions. The registration error was calculated automatically. Three observers tested the method independently.The inter-observer difference was investigated. An integratod model was selected randomly and the setup was creatod with roots and jaws in good relationship without fenestration and dehiscence.The individualized lingual brackets were designed by CAD on the setup. Results No significant difference was found in inter observers ( P ＞ 0.05 ).The registration errors of maxilla and mandible were ( 0.144 ±0.020) mm and (0.141 ±0.022 ) mm,respectively.The digital individualized lingual brackets based on the virtual treatment in integrated digital maxillodental model were produced. Conclusions An integrated digital maxillodental model was created in good accuracy. By applying the integrated model,individualized lingual brackets were designed.