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Influence of prior radiotherapy on free tissue transfer in head and neck region
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF STOMATOLOGY
- Issue:
- 2
- DOI:
- 10.3760/j.issn:1002-0098.2007.02.002
- Key Word:
- 外科皮瓣;放射肿瘤学;显微外科手术
Abstract： 目的 探讨术前放射治疗对头颈部游离组织瓣移植的成功率和术后并发症发生率的影响.方法 回顾分析1999年5月至2005年3月北京大学口腔医学院·口腔医院由同一手术小组完成的1007例患者的1066块头颈部游离瓣移植术,分别统计全部患者及术前放疗组和术前未放疗组游离组织瓣移植的成功率和术后并发症的发生率,并比较两组在游离瓣成功率和术后并发症发生率方面的差异.结果 1007例患者中,146例共计170块游离瓣有术前放射治疗史(放疗组),861例共计896块游离瓣无术前放疗史(未放疗组),放疗组游离瓣的成功率为97.6%,未放疗组游离瓣的成功率为98.4%,两者之间差异无统计学意义;放疗组的术后并发症发生率为38.4%,未放疗组的术后并发症发生率为36.4%,两者之间差异无统计学意义.除未放疗组有2例严重的供区并发症外,两组其余的并发症均不严重,未造成严重后果.结论 术前放射治疗并非是影响头颈部游离组织瓣移植成活的重要因素,正确选择游离瓣供区和受区血管,可靠的血管吻合技术,认真做好术前和术后处理,有助于减少游离瓣移植术后的并发症.
- [1]殷学民,邱蔚六,张陈平,等.应用吻合血管的骨肌皮瓣修复下颌骨放射性骨坏死[J].2005,(1).
- [2]Seungtaek, Choi,David L, Schwartz,D Greg, Farwell,etc.Radiation therapy does not impact local complication rates after free flap reconstruction for head and neck cancer.[J].2004,130(11).
- [3]B P, Bengtson,M A, Schusterman,B J, Baldwin,etc.Influence of prior radiotherapy on the development of postoperative complications and success of free tissue transfers in head and neck cancer reconstruction.[J].1993,166(4).
- [4]K, Aitasalo,M, Relander,E, Virolainen.Microvascular free tissue transfers after preoperative irradiation in head and neck reconstructions.[J].1997,529.
- [5]M A, Schusterman,M J, Miller,G P, Reece,etc.A single center's experience with 308 free flaps for repair of head and neck cancer defects.[J].1994,93(3).
- [6]Bhuvanesh Singh,Peter Cordeiro,Eric Santamaria,etc.Factors Associated with Complications in Microvascular Reconstruction of Head and Neck Defects[J].1999,103(2).
- [7]N F, Jones,J T, Johnson,K C, Shestak,etc.Microsurgical reconstruction of the head and neck: interdisciplinary collaboration between head and neck surgeons and plastic surgeons in 305 cases.[J].1996,36.
- [8]D A, Hidalgo,C S, Jones.The role of emergent exploration in free-tissue transfer: a review of 150 consecutive cases.[J].1990,86(3).
- [9]Joseph Serletti,James Higgins,Steven Moran,etc.Factors Affecting Outcome in Free-Tissue Transfer in the Elderly[J].2000,106(1).
- [10]D A, Hidalgo,J J, Disa,P G, Cordeiro,etc.A review of 716 consecutive free flaps for oncologic surgical defects: refinement in donor-site selection and technique.[J].1998,102.
- [11]D W, Stepnick,R E, Hayden.Postoperative monitoring and salvage of microvascular free flaps.[J].1994,27(6).