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Expression of mRNA of osteocalcin in condylar cartilage of young SD rats after functional protrusion
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF STOMATOLOGY
- Issue:
- 6
- DOI:
- 10.3760/j.issn:1002-0098.2001.06.002
- Key Word:
- 下颌骨髁状突;骨钙素;正畸
Abstract： 目的探讨生长发育期大鼠下颌髁突软骨中有无骨钙素mRNA的表达及其昼夜变化的规律.方法采用SD大鼠,应用原位杂交技术检测大鼠下颌髁突软骨中骨钙素mRNA的表达,以图像分析半定量研究骨钙素mRNA表达的昼夜变化规律.应用宏观、微观分析法进行统计分析.结果髁突软骨内有骨钙素mRNA的表达,峰值相位约在上午6时左右.戴用功能矫治器后骨钙素mRNA表达增强,其中24 h组升高幅度较12 h组明显.结论生长发育期大鼠下颌髁突软骨中骨钙素mRNA的表达呈现昼夜节律性.功能矫治后髁突软骨中骨钙素mRNA含量增加,24 h加力组增高的幅度均高于12 h组,说明戴用功能矫治器时间越长,效果越明显.
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