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Changes of elastase in gingival crevicular fluid after periodontal treatment of adult periodontitis patients
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF STOMATOLOGY
- Issue:
- 1
- DOI:
- 10.3760/j.issn:1002-0098.2000.01.005
- Key Word:
- 牙周炎;胰肽酶;龈沟液
Abstract： 目的 观察龈沟液(gingival crevicular fluid,GCF)中细胞外弹性蛋白酶(elastase in the supernatant,EA-s) 和细胞内弹性蛋白酶(elastase in the pellet,EA-p) 在牙周基础治疗后的变化.方法 用滤纸条的袋内取样法取8例患者43个牙位治疗前后的GCF样本,以底物检测法测定其中的EA-s及EA-p水平.结果 治疗后的GCF-EA-s、EA-p总量及EA-s浓度、EA-s/EA-p(S/P)比值均较治疗前显著下降(P＜0.001),但EA-p浓度治疗前后无显著差异(P＞0.05).结论 GCF-EA水平反映牙周组织的炎症破坏程度,可作为评价疗效的客观指标,尤其是EA-s和S/P的作用明显,二者在判断牙周组织的活动性破坏中有意义.
- [1]和璐,曹采方,沙月琴.龈沟液中弹性蛋白酶水平与白细胞数目的关系[J].1998,(6).
- [2]曹采方,Smit.,QT.龈沟液中髓过氧化酶活性与牙周病的关系[J].1989,024 (4).
- [3]B.M. Eley,S. W Cox.A 2-year longitudinal study of elastase in human gingival crevicular fluid and periodontal attachment loss[J].1996,23(7).
- [4]K G, Palcanis,I K, Larjava,B R, Wells,etc.Elastase as an indicator of periodontal disease progression.[J].1992,63.
- [5]沙月琴.低量强力霉素对牙周炎患者龈沟液胶原酶等活性的影响[J].1995,(5).
- [6]L.J. Jin,P.-Ö. Söder,B. Asman,etc.Granulocyte elastase in gingival crevicular fluid: improved monitoring of the site-specific response to treatment in patients with destructive periodontitis[J].1995,22(3).
- [7]Gustafsson, A.,Åsman, B.,Bergström, K..Altered relation between granulocyte elastase and α-2-macroglobulin in gingival crevicular fluid from sites with periodontal destruction.[J].1994,21(1).
- [8]S. W. Cox,B. M. Eley.Cathepsin B/L-, elastase-, tryptase-, trypsin- and dipeptidyl peptidase IV-like activities in gingival crevicular fluid[J].1992,19(5).