Pulse wave velocity, ankle-brachial index and carotid intima-media thickness measurement in the assessment of vascular status in elderly patients with isolated systolic hypertension

( views:193, downloads:0 )
Author:
YUAN Gong-xian(Department of Geriatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China)
WANG Hua(Department of Geriatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China)
REN Jiang-hua()
HUANG Cong-xin()
WANG Ying-hui()
Journal Title:
Chinese Journal of Health Management
Issue:
Volume 06, Issue 04, 2012
DOI:
10.3760/cma.j.issn.1674-0815.2012.04.004
Key Word:
Health management;Hypertension;Atherosclerosis;Blood pressure circadian rhythm

Abstract: Objective To evaluate the relation of circadian blood pressure rhythm with vascular status in elderly patients with isolated systolic hypertension.Methods Ankle-brachial index (ABI),brachial-ankle pulse wave velocity (baPWV) and carotid intima-media thickness (IMT) were measured in 74 elderly patients with non-dipper hypertension (non-dipper group)、78 elderly patients with dipper hypertension ( dipper group),and 72 healthy controls ( control group).Results In comparison with the dipper group,baPWV and IMT of the non-dipper group were significantly increased [ baPWV (1801.61± 314.27) vs (1658.67±274.80) (cm/s)],P<0.01; IMT:(0.96 ±0.22) vs (0.87 +0.19) (mm),(P<0.05),while ABI of the non-dipper group was decreased (1.03 ±0.17 vs1.12 ±0.18,P<0.01).Identification rate was significantly different among 3 groups when baPWV >1400 cm/s (x2 =12.57,P <0.01) or ABI <0.9 ( x2 =9.74,P <0.01).The detection of carotid plaques was also significantly different ( x2 =16.49,P < 0.01).Conclusions These findings suggest that vascular damage could be found in elderly patients with isolated systolic hypertension,especially in those with non-dipper hypertension.ABI,baPWV and IMT measurement may be helpful for the assessment of vascular status.

  • [1]中国高血压防治指南修订委员会.中国高血压防治指南2010年.中华心血管病杂志,2011,39:579-616.
  • [2]白书忠,武留信,陈刚.中国慢性非传染性疾病管理的目标与对策.中华健康管理学杂志,2009,3:323-328.
  • [3]武留信,陈刚,强东昌.慢性非传染性疾病风险因素管理的关键环节与核心技术.中华健康管理学杂志,2009,3:329-330.
  • [4]Mitchell GF,Hwang SJ,Vasan RS,et al.Arterial stiffness and cardiovascular events:the framingham heart study.Circulation,2010,121:505-511.
  • [5]Tanaka H, Munakata M, Kawano Y, et al.Comparison between.carotid-femoral and brachial-ankle pulse wave velocity as measures of arteral stiffness.J Hypertens,2009,27:2022-2027.
  • [6] Tsuchikura S,Shoji T,Kimoto E,et al.Brachial-ankle pulse wave velocity as an index of central arterial stiffness.J Artheroscler Thromb,2010,17:658-665.
  • [7]Wang DZ,Tang Q,Hua Q.Prediction of coronary artery disease using pulse wave velocity and retinal artery lesions.Tohoku J Exp Med,2011,225:17-22.
  • [8] Parr B,Noakes TD,Derman EW.Factors predicting walking intolerance in patients with peripheral arterial disease and intermittent claudication.S Afr Med J,2008,98:958-962.
  • [9]张岩,李建平.踝臂指数与冠心病的严重程度相关.北京大学学报:医学版,2011,43:749-752.
  • [10]安伟,李贤,王馨,等.高血压与外周动脉疾病的关系.北京大学学报:医学版,2010,42:667-670.
  • [11]毛勇,余金明,胡大一,等.多中心研究高血压患者心血管病危险度与踝臂指数异常的关联性.中华医学杂志,2011,91:2985-2989.
  • [12]强东昌,武留信,师绿江,等.健康体检人群脉搏波传导速度现状调查.中华健康管理学杂志,2010,4:275-278.
  • [13] Li CI,Kardia SL,Liu CS,et al.Metabolic syndrome is associated with change in subclinical arterial stiffness-a community-based taichung community health study.BMC Public Health,2011,11:808.
  • [14]Wittke E,Fuchs SC,Fuchs FD,et al.Association between different measurements of blood pressure variability by ABP monitoring and ankle-brachial index.BMC Cardiovasc Disord,2010,10:55.
  • [15]傅建梅,吴钢,辜秋阳.颈动脉弹性传递指数与原发性高血压患者颈动脉IMT的关联分析.中华神经医学杂志,2010,9:702-706.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn