Relationship between body mass index and left ventricular structure and function in young or middleaged men

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Author:
MENG Juan-juan(Health Examination Center, the First Affiliated Hospital of People's Liberation Army General Hospital, Beijing 100048, China)
TIAN Jing-fa(Health Examination Center, the First Affiliated Hospital of People's Liberation Army General Hospital, Beijing 100048, China)
LIU Jian(Health Examination Center, the First Affiliated Hospital of People's Liberation Army General Hospital, Beijing 100048, China)
Journal Title:
Chinese Journal of Health Management
Issue:
Volume 05, Issue 06, 2011
DOI:
10.3760/cma.j.issn.1674-0815.2011.06.006
Key Word:
Obesity;Echocardiography;Ventricular function,left

Abstract: Objective To investigate the relationship between body mass index(BMI)and cardiac structure and function of adult men living in Hebei province.Methods A total of 160 adults were assigned to 4 groups by BMI:normal body weight group(group A,BMI 18.5 to 23.9 kg/m2),overweight group (group B,BMI 24.0 to 27.9 kg/m2),mild obese group(group C,BMI 28.0 to 29.9 kg/m2),and severe obese group(group D,BMI ≥ 30 kg/m2).Left ventricular end-diastolic diameter(EDD),end-systolic diameter(ESD),inter ventricular septal thickness(IVS),left ventricular posterior wall thickness (LVPW),left ventricular mass(LVM),and left ventricular mass index(LVMI)were examined by echocardiography.Early(E)peak diastolic and late(A)diastolic mitral inflow velocity and E/A ratio were measured by Doppler echocardiography.Pulsed wave Doppler tissue image(PW-DTI)of the lateral mitral annulus was performed to evaluate early peak diastolic velocity(Em),late peak diastolic velocity(Am)and Em/Am ratio.Results Compared with group A,EDD,ESD,LNM,LVMI,Am,IVS and LVPW were increased in the other 3 groups(all P < 0.05).E,E/A ratio,Em,and Em/Am ratio were decreased in group B,C,and D(all P < 0.05).Compared with group B,Sm was decreased in group C and D(both P < 0.05).Conclusion Overweight and obesity could contribute to ventricular hypertrophy and deteriorate diastolic function in a BMI dependent manner.Obesity may be also related to decreased Sm.

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