Fatty liver development and changes of metabolic parameters

( views:131, downloads:0 )
Author:
WANG Sheng-hua(Medical Examination Center of Beijing Tongren Hospital,Beijing 100730,China)
REN Ji-ping(Medical Examination Center of Beijing Tongren Hospital,Beijing 100730,China)
WANG Zhao-ping(Medical Examination Center of Beijing Tongren Hospital,Beijing 100730,China)
LIANG Rong()
YANG Xin-yu()
Journal Title:
CHINESE JOURNAL OF HEALTH MANAGEMENT
Issue:
Volume 05, Issue 03, 2011
DOI:
10.3760/cma.j.issn.1674-0815.2011.03.005
Key Word:
Physical examinations;Fatty liver;Metabolic syndrome X

Abstract: Objective To investigate the relationship between fatty liver progress and metabolic changes.Methods A total of 414 patients who had B-mode ultrasonography confirmed fatty liver development during 2 health check-ups within 2 years were enrolled in this study.Paired t and χ2 tests were used to compare body mass index (BMI),alanine aminotransferase (ALT),aspartate aminotransferase (AST),fasting plasma glucose (FPG),serum uric acid (UA),triglycerides (TG),and high-density lipoprotein cholesterol (HDL-C) among the participants.Results BMI,TG,HDL-C,ALT,AST,and UA were significantly increased after fatty liver progressed,although HDL-C was largely decreased.ConclusionsPrevention and treatment of MS as well as early intervention for fatty liver should be important for successful control of fatty liver.

  • [1]张蔚韡,杜兵,罗克文,等.健康体检中脂肪肝发病率及相关因素分析.临床医学,2008,28:15-16.
  • [2]张建华,辛永宁,宣世英,等.非酒精性脂肪性肝病与代谢综合征的相关性分析.实用医学杂志,2009,25:1229-1230.
  • [3]陈一奕,范竹萍,茅益民,等.非酒精性脂肪性肝病与代谢综合征的流行现状及相关性研究.肝脏,2008,13:456-458.
  • [4]观晓辉,范碧惠,李韶光.成人非酒精性脂肪性肝病与代谢综合征关系.中国公共卫生,2009,25:829-830.
  • [5]中华医学会肝脏病学分会脂肪肝和酒精性肝病学组.非酒精性脂肪性肝病诊疗指南.中华肝脏病杂志,2006,14:161-163.
  • [6]Farrell GC,Chitturi S,Lau GK,et al.Guidelines for the assessment and management of non-alcoholic fatty liver disease in the Asia-Pacific region:executive summary.J Gastroenterol Hepatol,2007,22:775-777.
  • [7]中华医学会风湿病学会.原发性痛风诊治指南(草案).中华风湿病学杂志,2004,8:178-181.
  • [8]周英.脂肪肝与体重质量指数、血脂水平的相关性探讨.医学综述,2005,8:762.
  • [9]赵兰江,赵冬.尿酸代谢异常与甘油三脂代谢异常的关系.中华流行病学杂志,2006,27:362-365.
  • [10]何权瀛.应当重视肥胖及其相关疾病的控制.中华健康管理学杂志,2010,4:132-133.
  • [11]刘彦君,肖婷,朱平,等.减轻体重对伴有糖耐量受损的超重及肥胖者代谢指标的影响.中华健康管理学杂志,2010,4:142-144.
  • [12]陈庆瑜,陈超刚,廖蓓,等.减重干预对超重与肥胖成人代谢指标的影响.中华健康管理学杂志,2010,4:223-226.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn