The effects of health education and comprehensive lifestyle modification on postmenopausal osteoporosis women treatment with alendronate sodium

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Author:
LIN Hua(The Center of Research for Metabolic Bone Disease, The Affiliated Drum Tower Hospital of Medical School, Nanjing University, Nanjing 210008, China)
CHEN Xin(The Center of Research for Metabolic Bone Disease, The Affiliated Drum Tower Hospital of Medical School, Nanjing University, Nanjing 210008, China)
ZHU Xiu-fen(The Center of Research for Metabolic Bone Disease, The Affiliated Drum Tower Hospital of Medical School, Nanjing University, Nanjing 210008, China)
FAN Lu(The Center of Research for Metabolic Bone Disease, The Affiliated Drum Tower Hospital of Medical School, Nanjing University, Nanjing 210008, China)
WU Qiu-hua()
Journal Title:
CHINESE JOURNAL OF HEALTH MANAGEMENT
Issue:
Volume 05, Issue 01, 2011
DOI:
10.3760/cma.j.issn.1674-0815.2011.01.002
Key Word:
Osteoporosis;Bone density;Life style;Education;Health management

Abstract: Objective To evaluate the effects of an intervention programme of health education and life style modification on postmenopausal osteoporosis women. Methods A total of 120 postmenopausal osteoporosis women were enrolled in this one-year randomized controlled follow-up study and assigned to the intervention group ( Group A, n = 60) or the control group ( Group B, n = 60). Both groups were treated with alendronate sodium. In Group A, education program was performed once a season in the form of face-to-face consultation or group session. In Group B, no additional intervention was used. The primary outcome was patients' compliance in follow-up. The secondary outcomes were change in bone mineral density (BMD).BMD was measured by dual-X-ray absorptiometry (DXA) on lumbar spine and hip at baseline and 12 months after the intervention. Results After one-year intervention,51 subjects in Group A and 38 in Group B completed the follow-up. Groups A showed better compliance. BMD on lumbar spine and hip was significantly increased in both groups when compared with baseline. The changes of BMD on lumbar (0.042+0.067 vs 0.026±0.070,P=0. O29) or Words region (0.029 +0. 129 vs 0.023±0. 143,P=0. 041 ) showed statistical significance between the two groups. Conclusion For alendronate sodium treatment, health management ensures the effectiveness of the therapy and improves the compliance of the patients.

  • [1]白书忠,武留信,陈刚.中国慢性非传染性疾病管理的目标与对策.中华健康管理学杂志,2009,3:323-328.
  • [2]林华,吴秋华,柳剑,等.生活方式干预常见慢性非传染性疾病高危人群的初步研究.中华健康管理学杂志,2008,2:95-98.
  • [3]Winzenberg T,Oldenburg B,Frendin S,et al.The effect on behavior and bone mineral density of individualized bone mineral density feedback and educational interventions in premenopausal women:a randomized controlled trial.BMC Public Health,2006,6:12-24.
  • [4]林华,陈新,朱秀芬,等.绝经后骨质疏松高危人群的健康管理干预.中华骨质疏松和骨矿盐疾病杂志,2009,2:93-98.
  • [5]Lock CA,Lecouturier J,Mason JM,et al.Lifestyle interventions to prevent osteoporotic fractures:a systematic review.Osteoporos Int,2006,17:20-28.
  • [6]林华,陈新,朱秀芬,等.健康管理干预绝经后骨质疏松及其高危人群的研究.中华健康管理学杂志,2009,3:336-340.
  • [7]Black DM,Kelly MP,Genant HK,et al.Bisphosphonates and fractures of the subtrochanteric or diaphyseal femur.N Engl J Med,2010,362:1761-1771.
  • [8]Schwarz U.The Hypertension Paradox.N Engl J Med,2009,61:2195-2196.
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