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Effect of simulated saturation diving on immune function of T lymphocyte in mice

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF NAUTICAL MEDICINE AND HYPERBARIC MEDICINE
Issue:
2
DOI:
10.3760/cma.j.issn.1009-6906.2008.02.004
Key Word:
饱和潜水;T淋巴细胞;流式细胞术;细胞免疫;Saturation diving;T lymphocyte;Flow cytometry;Cell immunity

Abstract: Objective To investigate effect of simulated saturation diving on immune function of T lymphocyte in mice.Methods Thirty Kunming-race mice were randomly divided into 5 groups:control group,at 100 m simulated saturation diving exposure for 24 h and 72 h groups,at 400 m simulated saturation diving exposure for 24 h and 72 h groups,each group for 6 mice.The T lymphocyte subsets of peripheral blood,collected 10 minutes after exposure,were assayed by flow cytometry.Results The level of CD4+ lymphocyte and CD4+/CD8+ ratio tended to increase after exposure at 100 m,while the levels of CD4+ lymphocyte and CD4+/CD8+ significantly decreased after exposure at 400 m.Conclusions The effect of simulated saturation diving on cellular immune function was correlated significantly with exposed pressure.

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