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Application of EEG in the research of oxygen-induced convulsion in mice
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF NAUTICAL MEDICINE AND HYPERBARIC MEDICINE
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1009-6906.2005.03.006
- Key Word:
- 脑电图;氧惊厥;小鼠
Abstract： 目的观察小鼠氧惊厥及惊厥后脑电图的改变.方法小鼠头部预先埋置电极,进行舱内高压氧(HBO)暴露,动态观察记录氧惊厥小鼠脑电改变以及暴露后脑电恢复情况. 结果小鼠埋置电极3～5 d后脑电改变恢复正常,舱内HBO暴露致氧惊厥时脑电图发生类似癫痫大发作时的痫波变化,并在氧暴露撤离后7 d左右脑电图改变恢复正常.结论脑电图记录在小鼠氧惊厥研究中是一种可行、客观和稳定的方法.
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