A comparison of the different CT scanning modes on the GTV delineation of the solitary pulmonary lesion

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Author:
SHANG Dong-ping(Department of Radiation Oncology, Shandong Tumor Hospital and Institute;Shandong Province Key Laboratory of Radiation Oncology Ji'nan 250117, China)
WANG Wei(Department of Radiation Oncology, Shandong Tumor Hospital and Institute;Shandong Province Key Laboratory of Radiation Oncology Ji'nan 250117, China)
LI Jian-bin(Department of Radiation Oncology, Shandong Tumor Hospital and Institute;Shandong Province Key Laboratory of Radiation Oncology Ji'nan 250117, China)
WANG Yun-gang(Department of Radiation Oncology, Shandong Tumor Hospital and Institute;Shandong Province Key Laboratory of Radiation Oncology Ji'nan 250117, China)
ZHANG Ying-jie(Department of Radiation Oncology, Shandong Tumor Hospital and Institute;Shandong Province Key Laboratory of Radiation Oncology Ji'nan 250117, China)
LI Yan-chi(Department of Radiation Oncology, Shandong Tumor Hospital and Institute;Shandong Province Key Laboratory of Radiation Oncology Ji'nan 250117, China)
DU Jun(Department of Radiation Oncology, Shandong Tumor Hospital and Institute;Shandong Province Key Laboratory of Radiation Oncology Ji'nan 250117, China)
Journal Title:
Chinese Journal of Radiation Oncology
Issue:
Volume 21, Issue 05, 2012
DOI:
10.3760/cma.j.issn.1004-4221.2012.05.013
Key Word:
Tomography, X-ray computed;Lung neoplasms, solitary lesion;Gross tumor volume

Abstract: Objective To explore the influence of the CT scanning mode on the gross tumor volume (GTV) delineation of solitary pulmonary lesion (SPL),and to evaluate the feasibility of the spiral CT scan in CT simulation.Methods Sixteen patients with SPL underwent axial scan,spiral scan during free breathing.Compare the target position,volume between GTVS and GTVA (paired t-test).The matching index (MI) between GTVS and GTVA and correlations between MI and the tumor volume were calculated ( bivariate correlation analysis).Results GTVS and GTVA volume was 8.95 cm3 and 9.38 cm3 ( t =0.43,P =0.667),respectively.The centroid position for GTVS and GTVA in x,y and z axises were 6.80 cm and 6.81 cm (t =0.27,P =0.794),36.19 cm and 36.05 cm (t =0.37,P =0.717),and 4.99 cm and 4.96cm (t =0.65,P =0.526),respectively.There were also no statistically significant difference in the distance between the centroidal position and origin of coordinates for GTVS and GTVA (38.31 cm∶ 38.23 cm,t =0.47,P =0.646 ).MI between GTVS and GTVA was 0.36 ( range 0-0.77 ),correlated with the tumor volume (r =0.587,P =0.017).Conclusions There was no significant difference between the axial scan and spiral scan in the GTV volume and position for SPL,but MI between GTVS and GTVA were small.A correlation was found for the MI between GTVS and GTVA with the tumor volume.Spiral CT scan was more timesaving,and was feasible in CT simulation scan.

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