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Potential role of 18FDG PET-CT for target volume definition of metastatic lymph nodes in advanced esophageal carcinoma
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 1
- DOI:
- 10.3760/j.issn:1004-4221.2007.01.003
- Key Word:
- 食管肿瘤;淋巴结转移/放射疗法;氟脱氧葡萄糖;正电子发射型,体层摄影术;图像融合;大体肿瘤靶体积;临床靶体积
Abstract： 目的 分析18FDG PET-CT诊断食管癌淋巴结转移的优势及确定淋巴结放疗靶区的可行性.方法 回顾性分析30例食管癌患者的临床病理资料,分析PET-CT在诊断淋巴结转移方面的优势,基于CT和PET-CT确定淋巴结大体肿瘤靶区(GTVN)和临床靶区(CTVN),根据术后病理分析PET-CT在确定淋巴结放疗靶区中的价值.结果 13例由CT确定的GTVN(GTVN-CT)与病理一致,19例基于PET-CT的GTVN(GTVN-PET-CT)与病理相符.对照淋巴结病理结果,PET-CT改变了15例由CT确定的GTVN和其中10例的CTVN.PET-CT导致GTV缩小(GTVN-PET-CT＜GTVN-CT)的3例共涉及3组淋巴结,其中1例临床靶区缩小(CTVN-PET-CT＜CTVN-CT);GTVN-PET-CT＞GTVN-CT的12例共涉及22组淋巴结,其中9例CTVN亦扩大.GTVN-PET-CT＞GTVN-CT的亚组分析显示,PET-CT确定的淋巴结GTV准确率高于CT(67%:25%,P=0.041).结论 PET-CT在诊断淋巴结转移中的优势使之可作为优化和确定食管癌淋巴结放疗靶区的有用工具.
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