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Dosimetry study of intensity modulated radiation therapy for left side breast cancer
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1004-4221.2006.03.009
- Key Word:
- 乳腺肿瘤/外科学;部分乳房切除术;乳腺肿瘤/放射疗法;调强放射疗法;心脏/剂量学;乳腺/剂量学
Abstract： 目的比较左侧乳腺癌保乳术后调强放疗与常规放疗靶区内剂量均匀性、心脏照射剂量和体积的差异.方法对38例左侧乳腺癌保乳术后,应用逆向调强计划,实施全乳腺两野调强放疗.处方剂量为靶区X线46Gy,瘤床应用常规电子线追加14Gy,总量为60Gy.在同一病例CT片上设计常规全乳切线野照射46Gy.在两种治疗方法剂量体积直方图上比较靶区和心脏受照剂量.应用SPSS11.0软件进行配对T检验,以确定调强放疗是否可改善靶区内剂量均匀度并减少心脏受照剂量.结果调强放疗、常规放疗计划中CTV的D95分别为(4541±34)、(4517±62)cGy,V105%分别为17.5%±17.6%、29.4%±26.3%(P＜0.01);V110%分别为0.3%±0.8%和3.7%±8.2%(P=0.010).心脏的V30分别为4.6%±4.3%、18.8%±12.2%(P＜0.01);V40分别为1.4%±2.3%、14.3%±11.0%(P＜0.01).结论左侧乳腺癌保乳术后,调强放疗能改善靶区剂量分布、减少心脏受照剂量和体积.
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