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Retrospective analysis on results of late course accelerated hyperfractionation radiotherapy and conventional fractionation radiotherapy plus brachytherapy for esophageal carcinoma
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1004-4221.2006.03.006
- Key Word:
- 食管肿瘤/放射疗法;放射剂量分次;食管肿瘤/近距离放射宁法;预后
Abstract： 目的回顾分析和比较后程加速超分割放疗(后超组)与常规分割+腔内放疗(腔内组)食管癌的疗效.方法对1994年5月至1999年11月间4个小样本前瞻性研究的后超组(135例)和腔内组(130例)治疗食管癌的病例进行分析比较.后超组前3周常规分割照射3000cGy(分15次3周完成),后2周采用加速超分割照射3000 cGy(分20次2周完成;150 cGy/次,2次/d,2次相隔6 h,5d/周).腔内组常规分割照射5000 cGy(分25次5周完成)+腔内照射1000 cGy(分2次).结果后超组和腔内组1、3、5年总生存率分别为61.8%、27.9%、19.9%和53.5%、25.2%、18.4%(P＞0.05).后超组和腔内组急性放射性食管炎的发生率分别为61.5%和57.0%(P=0.235),且RTOG分级3级食管炎比较两组差异也无统计学意义.结论两种放疗方式食管癌的生存率无明显差别,但后程加速超分割技术操作方便,易于在临床中实施.
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