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Prognostic factors of maxillary sinus epithelial carcinoma
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 5
- DOI:
- 10.3760/j.issn:1004-4221.2005.05.001
- Key Word:
- 上颌窦肿瘤/外科学;上颌窦肿瘤/放射疗法;综合疗法;预后
Abstract： 目的探讨上颌窦癌的临床病理特征与预后的关系.方法 124例上颌窦癌中放疗40例,手术治疗18例,放疗+手术治疗66例.生存率计算采用Kaplan-Meier法,生存率差异比较采用Logrank检验,多因素分析采用Cox模型.结果 5年总生存率、癌症相关生存率和无进展生存率分别为32.5%、37.4%和27.2%.单因素分析显示,肿瘤位置、病理类型、T分期、淋巴结转移情况、临床分期和治疗方式与癌症相关生存(CSS)和无进展生存(PFS)均有相关性;而年龄仅与CSS相关,而与PFS无关.多因素分析显示,病理类型、T分期、临床分期和治疗方式是影响预后的独立因素.结论T分期和临床分期是影响上颌窦癌预后的重要因素.对T3～T4期即使淋巴结阴性上颌窦鳞癌,予以颈部预防性照射也是必要的.上颌窦癌的最佳治疗模式仍有待进一步研究.
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