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Prelimiary results of three-dimensional conformal radiotherapy for non-small cell lung cancer
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 4
- DOI:
- 10.3760/j.issn:1004-4221.2005.04.002
- Key Word:
- 癌,非小细胞肺/放射疗法;三维适形放射疗法;放射性肺炎;放射性食管炎
Abstract： 目的分析三维适形放疗(3DCRT)在非小细胞肺癌(NSCLC)治疗中的效果和放射损伤情况,并分析其预后因素.方法接受3DCRT的91例NSCLC中男73例,女18例,中位年龄66岁.放疗中位单次剂量2Gy,5次/周,中位总剂量60Gy,中位随访期17个月.结果完全缓解11.0%(10/91),部分缓解46.2%(42/91),稳定33.0%(30/91),进展1.1%(1/91),有效率57.1%(52/91).1、2年总生存率分别为67.0%、32.6%,中位生存期16个月.1、2年的无局部进展生存率分别为82.6%、53.0%.单因素和多因素分析都显示,体重下降≥5%预后不良.急性放射性肺炎2级2例,3级4例;晚期放射性肺炎2级1例,3级1例.急性放射性食管炎2级8例.急性2级骨髓毒性5例.结论3DCRT治疗NSCLC有很好的近期疗效,放射损伤在可接受范围.放疗总剂量还有提升的空间.
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