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Value of 18FDG PET-CT in detecting the metastatic mediastinal lymph node in non-small cell lung cancer
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1004-4221.2005.03.005
- Key Word:
- 癌,非小细胞肺;淋巴结转移;体层摄影术,发射型计算机;体层摄影术,X线计算机;诊断显像
Abstract： 目的通过对非小细胞肺癌(NSCLC)患者纵隔淋巴结术前氟脱氧葡萄糖(18FDG)PET-CT检查和术后病理结果比较,探讨18FDGPET-CT在判断NSCLC纵隔淋巴结转移(淋巴结短径＜10mm)方面的作用与价值.方法12例经病理确诊的NSCLC患者术前行18FDG PET-CT检查,详细记录纵隔淋巴结转移情况,主要探讨短径＜10 mm的纵隔淋巴结转移情况.术后病理结果作为金标准对纵隔淋巴结转移情况进行验证.可以做分析的淋巴结共有76个.结果76个淋巴结中,病理证实为阳性6个,病理证实为阴性的70个.PET-CT共检出5个真阳性、67个真阴性、3个假阳性、1个假阴性淋巴结.PET-CT的敏感性为83.3%,特异性为95.7%,准确性为94.7%.阳性预测值为62.5%,阴性预测值为98.6%.结论18FDG PET-CT对短径＜10 mm的纵隔淋巴结是否转移的判断是准确和可信的,对NSCLC患者治疗方案的制订有较高的临床价值.
- [1]于金明.二十一世纪的放射肿瘤学[J].2002,(6).
- [2]Albes JM,Ziemer G,Schulen E,etc.Value of positron emission tomography for lung cancer staging.[J].2002,28(1).
- [3]Rosenzweig KE,Sim SE,Mychalczak B,etc.Elective nodal irradiation in the treatment of non-small-cell lung cancer with three-dimensional conformal radiation therapy.[J].2001,50(3).
- [4]T E, Williams,C R, Thomas,A T, Turrisi.Counterpoint: better radiation treatment of non-small cell lung cancer using new techniques without elective nodal irradiation.[J].2000,10(4).
- [5]Fazio F,Rizzo G,Messa C,etc.FDG/PET and spiral CT image fusion for medistinal lymph node assessment of non-small cell lung cancer patients.[J].1999,40(5).
- [6]Hashimoto S,Tsukamoto E,Kato T,etc.Image fusion between 18FDG-PET and MRI/CT for radiotherapy planning of oropharyngeal and nasopharyngeal carcinomas.[J].2002,53(4).
- [7]V, Liengswangwong,J A, Bonner.Point: the potential importance of elective nodal irradiation in the treatment of non-small cell lung cancer.[J].2000,10(4).
- [8]Taylor TM,Segel LD,Shelton D,etc.Advantages of positron emission tomography over computed tomography in mediastinal staging of non-small cell lung cancer.[J].2002,103(2).
- [9]M R, Roman,M A, Rossleigh,S, Angelides,etc.Staging and managing lung tumors using F-18 FDG coincidence detection.[J].2001,26.
- [10]N C, Gupta,W J, Tamim,G G, Graeber,etc.Mediastinal lymph node sampling following positron emission tomography with fluorodeoxyglucose imaging in lung cancer staging.[J].2001,120(2).
- [11]Thomas A, D'Amico,Terence Z, Wong,David H, Harpole,etc.Impact of computed tomography-positron emission tomography fusion in staging patients with thoracic malignancies.[J].2002,74(1).
- [12]Friedel G,Paulsen F,Dohmen BM,etc.FDG PET for staging of advanced non-small cell lung cancer prior to neoadjuvant radio-chemotherapy[J].2002,29(6).
- [13]Brink I,Nitzsche E,Stoelben E,etc.Validation of FDG positron emission tomography for differentiation of unknown pulmonary lesions.[J].2001,20(2).
- [14]Jeffrey D, Bradley,Sasha, Wahab,Mary Ann, Lockett,etc.Elective nodal failures are uncommon in medically inoperable patients with Stage I non-small-cell lung carcinoma treated with limited radiotherapy fields.[J].2003,56.