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Influence of 18F-deoxyghucose γ-camera PET imaging on the treatment of non-small cell lung cancer
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 1
- DOI:
- 10.3760/j.issn:1004-4221.2005.01.005
- Key Word:
- 体层摄影术,发射型计算机,γ-相机型;氟脱氧葡萄糖;癌,非小细胞肺;肿瘤分期;肺不张
Abstract： 目的探讨氟脱氧葡萄糖γ-相机型PET(hPET)显像与常规检查相结合对非小细胞肺癌(NSCLC)临床分期的影响,以及由此产生的对治疗策略和放疗靶区的影响.方法49例经病理证实初治的NSCLC、有完整病史、体检和临床分期检查者进入研究.在做hPET前根据病史、临床检查及常规影像学检查进行临床分期并制定一治疗方案.hPET检查后结合其结果重新进行临床分期,再制定一治疗方案,比较在有和没有hPET参与的情况下的临床分期差别以及分期改变对治疗决策的影响,并比较其中伴肺不张者CT和hPET所显示原发肿瘤体积的差异.结果49例中hPET检查前准备行根治性治疗22例,姑息性治疗27例.hPET检查后36.7%(18/49)临床分期有改变,其中分期上升5例,下降13例.36.7%(18/49)治疗决策有变化.对伴肺不张者hPET图像显示肿瘤体积比CT所显示的肿瘤体积平均小17.7%.结论hPET的参与显著影响了NSCLC的临床分期和治疗策略的确定.对伴肺不张者,hPET有望鉴别肺不张和肿瘤.
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