You Position: Home > Paper
Remote results of radiotherapy for primary orbital lymphoma
( views:277, downloads:60 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 4
- DOI:
- 10.3760/j.issn:1004-4221.2004.04.003
- Key Word:
- 眼眶肿瘤/放射疗法;淋巴瘤/放射疗法;预后
Abstract： 目的分析眼眶原发淋巴瘤的疗效及影响预后的因素.方法44例经病理证实的眼眶原发淋巴瘤,男女之比为1.6:1.原发在眼睑结膜的27例,中位年龄44岁;原发在眼眶的17例,中位年龄62岁.双侧同时发病4例.Ⅰ A期40例,ⅡA期4例.采用常规外照射放射治疗,先用60Co γ射线全眼眶区照射30～35 Gy后用60Coγ射线、180 kV X线或9 MeV电子线进行肿瘤区照射,中位剂量46.5 Gy.结果全部病例的5、10年生存率分别为90.9%、84.5%.眼睑结膜病例的5年生存率明显高于眼眶者(96.3%:70.6%,P=0.013).临床分期为Ⅰ期病例生存时间明显长于Ⅱ期者(P=0.000).结论眼眶淋巴瘤的复发少、长期预后佳,放射剂量一般不宜超过40 Gy.结膜来源的眼睑结膜淋巴瘤与泪腺来源的眼眶淋巴瘤可能是两种临床特点与预后不同的类型.眼眶淋巴瘤是一种容易多发的疾病.放射治疗前肿块手术切除意义不大.
- [1]孙亚斌,魏锐利,赵岳峰.眼眶原发粘膜相关淋巴组织淋巴瘤临床分析[J].2002,(9).
- [2]王绿化,顾大中,黄一蓉.眼眶原发恶性淋巴瘤的放射治疗[J].1999,(3).
- [3]Cox JD,Cabanillas FF,Pelloski CE,etc.Clinical stage IEA-IIEA orbital lymphomas: outcomes in the era of modern staging and treatment.[J].2001,59(2).
- [4]Buatti J,Wen B,Paulino A,etc.Curative radiotherapy for primary orbital lymphoma.[J].2002,54(3).
- [5]O, Esik,H, Ikeda,K, Mukai,etc.A retrospective analysis of different modalities for treatment of primary orbital non-Hodgkin's lymphomas.[J].1996,38.
- [6]M C, Smitt,S S, Donaldson.Radiotherapy is successful treatment for orbital lymphoma.[J].1993,26.
- [7]Hoppe RichardT,Le QuynhThu,Warnke RogerA,etc.Primary radiotherapy for localized orbital MALT lymphoma.[J].2002,52(3).
- [8]Stafford SL,Kozelsky TF,Leavitt JA,etc.Orbital lymphoma: radiotherapy outcome and complications.[J].2001,59(2).
- [9]J G, Letschert,D, González González,J, Oskam,etc.Results of radiotherapy in patients with stage I orbital non-Hodgkin's lymphoma.[J].1991,22.
- [10]Miralbell R,Scandolaro L,Maingon P,etc.Outcome and prognostic factors in orbital lymphoma. a Rare Cancer Network study on 90 consecutive patients treated with radiotherapy.[J].2003,55(4).