You Position: Home > Paper
Logistic regression analysis on the risk factors of radiation pneumonitis
( views:886, downloads:617 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- z1
- DOI:
- 10.3760/j.issn:1004-4221.2003.z1.004
- Key Word:
- 肺肿瘤/放射疗法;放射性肺炎;因素分析,统计学;Logistic回归
Abstract： 目的探讨放射性肺炎发生的影响因素,以指导肺癌治疗计划的制定,避免和减少正常肺组织的放射损伤.方法选取101例放射性肺炎患者,研究照射剂量等20个因素与放射性肺炎的关系.应用SPSS*!8.0进行χ2检验的单因素分析、Logistic多元回归分析筛选影响因素.结果①单因素分析显示肺部感染、肺不张、阻塞性肺炎、胸水、心血管疾患、慢性支气管炎史、化疗史、照射剂量、照射天数、照射野大小10个因素与放射性肺炎的发生有关.②多因素研究发现肺部感染、阻塞性肺炎、肺不张、胸水、慢性支气管炎史、心血管疾患、化疗史、照射剂量、照射野大小9个因素为放射性肺炎发生的独立影响因素.结论在制定肺癌放射治疗计划时,充分考虑患者的合并症、化疗史、照射剂量、照射野大小等因素,可减少放射性肺炎的发生机会.
- [1]谷铣之.肿瘤放射治疗学[M].1994.
- [2]廖颖曦,李高峰.胸部放疗与放射性肺炎[J].1997,(2).
- [3]M, Roach,D R, Gandara,H S, Yuo,etc.Radiation pneumonitis following combined modality therapy for lung cancer: analysis of prognostic factors.[J].1995,13.
- [4]申文江,1939-,王绿化(医学).放射治疗损伤[M].2001.
- [5]M. Yamada,S. Kudoh,K. Hirata,etc.Risk factors of pneumonitis following chemoradiotherapy for lung cancer[J].1998,34(1).
- [6]Y, Segawa,N, Takigawa,M, Kataoka,etc.Risk factors for development of radiation pneumonitis following radiation therapy with or without chemotherapy for lung cancer.[J].1997,39.
- [7]G, Müller,I C, Kiricuta,J, Stiess,etc.[Radiation pneumonitis and pulmonary fibrosis after the CT-planned radiotherapy of bronchial carcinoma].[J].1994,170.
- [8]P, Schraube,R, Schell,M, Wannenmacher,etc.[Pneumonitis after radiotherapy of bronchial carcinoma: incidence and influencing factors].[J].1997,173.
- [9]Robnett TJ,Machtay M,Vines EF,etc.Factors predicting severe radiation pneumonitis in patients receiving definitive chemoradiation for lung cancer.[J].2000,48(1).