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Significance of postoperative radiotherapy for thymoma: analysis of 106 patients
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 4
- DOI:
- 10.3760/j.issn:1004-4221.2003.04.005
- Key Word:
- 胸腺瘤/外科学;胸腺瘤/放射疗法;预后
Abstract： 目的探讨胸腺瘤术后放射治疗的临床价值.方法对106例接受手术或术后放射治疗的胸腺瘤患者做回顾性分析,按Masaoka临床分期,Ⅰ期32例,Ⅱ期30例,Ⅲ期36例,Ⅳ期8例.完全切除66例,次全切除28例,不能切除而行活检探查12例.其中Ⅰ期完全切除12例,Ⅱ期完全切除14例,Ⅲ期完全切除2例、次全切除26例、探查活检4例和Ⅳ期探查活检8例;共66例术后行放射治疗.结果全组总5年生存率为73.6%,完全切除66例和次全切除28例的5年生存率分别为 89.4%和53.6%(P=0.025),Ⅰ期单纯手术20例和术后放射治疗12例的5年生存率分别为95.0%和91.2%(P=0.876).Ⅱ、Ⅲ期术后放射治疗的5年生存率分别为87.6%、68.8%,与单纯手术的 50.0%和25.0%比较差异有显著性意义(P值分别为0.042、0.035).结论术后放射治疗可以提高Ⅱ、Ⅲ期患者生存率,胸腺瘤Ⅰ期术后行常规放射治疗无临床意义.
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