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Radiotherapy and prognosis of 109 patients with oligodendroglioma
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIATION ONCOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1004-4221.2003.03.004
- Key Word:
- 脑肿瘤/外科学;脑肿瘤/放射疗法;预后
Abstract： 目的总结脑少突胶质细胞瘤的治疗效果,评价影响生存的因素.方法对109例病理诊断为少突胶质细胞瘤的患者进行回顾性分析,其中单纯少突胶质细胞瘤Ⅱ级38例、Ⅲ级23例,少突-星型胶质细胞混合瘤Ⅱ级30例、Ⅲ级18例.13例行肉眼完全切除术,54例为部分切除术,余42例为单纯活检术.所有患者均在术后行6～15 MV X射线常规放射治疗.生存分析采用Kaplan-Meier法及Logrank检验,多因素分析采用Cox 回归模型.结果 5、10年肿瘤无复发生存率和累积生存率分别为47.2%、33.6%和53.8%、39.1%.单因素分析结果显示年龄<50岁、病理分级低(Ⅱ级)、在CT或(和)MRI影像上病变无增强、行肿瘤完全切除术的患者预后较好,而病变在CT或(和)MRI影像增强情况在多因素分析中则不再有意义.结论年龄、病理分级和手术的切除程度是影响少突胶质细胞瘤预后的独立因素.
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