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The risk factors of cervical lymph node recurrence after radiotherapy for neck n egative nasophargneal carcinoma.

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Author:
No author available
Journal Title:
ZHONGHUA FANGSHE ZHONGLIUXUE ZAZHI
Issue:
1
DOI:
10.3760/j.issn:1004-4221.2001.01.003
Key Word:
鼻咽肿瘤/放射疗法;颈淋巴结,复发;预后

Abstract: Objective To analyze the risk factors of cervical lymph node recurren ce in N0 nasopharyngeal carcinoma (NPC).  Methods From January 1987 to December 1 996, 211 NPC patients without cervical lymph node involvement were treated with radiotherapy alone. Retrospective univariate and multivariate analyses were perf  Results  Forty-nine patients of these 211 patients deve lo ped recurrence in the cervical lymph nodes. The cervical lymph node recurrence r ate was lower in patients treated with conjoint facio-cervical fields to > 50 Gy in the upper neck as compared to those treated with seperate facial and neck fields to <50 Gy in the upper neck (P=0.000). The parapha ryng eal involvement a nd high T stage lesion are risk factors for neck node recurrence (P=0.001 and P=0.003 ). The neck recurrence in patients who received prophylactic whole neck irradiat ion was lower than those who received prophylactic upper neck irradiat ion(P>0.05) Conclusions We suggest that patients with neck negative NPC shou ld be treated with conjoint facio-cervical lateral fields and prophylactic w hole neck irradiation with more than 50 Gy to the upper neck.

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