You Position: Home > Paper

FDG PET imaging in the follow-up of nasopharyngeal carcinoma

( views:324, downloads:24 )
Author:
No author available
Journal Title:
ZHONGHUA FANGSHE ZHONGLIUXUE ZAZHI
Issue:
1
DOI:
10.3760/j.issn:1004-4221.2001.01.002
Key Word:
鼻咽肿瘤/放射疗法;FDG PET;CT;MRI

Abstract: Objective To investigate the clinical value of FDG PET imaging in the follow-up of nasopharyngeal carcinoma after radiotherapy.  Methods Twelve patients with nasopharyngeal carcinoma underwent FDG PET, CT and/or MRI during the follow-up of 12-18 months after radiotherapy. The results of FDG PET were double-blind evaluated and compared with these of CT and MRI. The recurrent lesions in six of these patients were pathologically confirmed and six by CT scan.  Results Nine of 12 patients did not show any recurrence by CT and MRI scans. However, FDG PET scans showed significantly increased FDG metabolism, indicating recurrence in 3 of these patients. In 2 patients, both CT/MRI and FDG PET indicated recurrence. The remaining one patient had radiotherapy induced cerebral necrosis. He was misdiagnozed as an intracranial recurrence by MRI, but FDG imaging was negative.  Conclusions FDG PET imaging has an advantage in distinguishing the relapse or necrosis in the follow-up of post-radiotherapy nasopharyngeal carcinoma patients. PET, CT and MRI is able to give a detail both in morphological and functional changes of disease. They are especially useful in the follow-up or the set-up of treatment planning for recurrent nasopharyngeal carcinoma.

WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn