Study of abdominal CT angiography in low tube voltage setting combined with personalized contrast media application

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Author:
CAO Jian-xin(Department of Radiology, PLA 161th Hospital, Wuhan 430010, China)
WANG Yi-min(Department of Radiology, PLA 161th Hospital, Wuhan 430010, China)
ZHANG Yu(Department of Radiology, PLA 161th Hospital, Wuhan 430010, China)
TAO Wei(Department of Radiology, PLA 161th Hospital, Wuhan 430010, China)
ZHANG Xiao-dong(Department of Radiology, PLA 161th Hospital, Wuhan 430010, China)
WANG Ai-jun(Department of Radiology, PLA 161th Hospital, Wuhan 430010, China)
LIU Li(Department of Radiology, PLA 161th Hospital, Wuhan 430010, China)
WANG Peng(Department of Radiology, PLA 161th Hospital, Wuhan 430010, China)
Journal Title:
Chinese Journal of Radiology
Issue:
Volume 46, Issue 10, 2012
DOI:
10.3760/cma.j.issn.1005-1201.2012.10.007
Key Word:
Tomography, X-ray computed; Radiation dosage; Contrast media

Abstract: Objective To investigate the feasibility of decreasing radiation dose and contrast media dose of abdominal CTA using low tube voltage setting combined with personalized contrast media application.Methods One hundred and twenty patients were randomly divided into 3 groups,and there were 40 patients in each group.120 kV tube voltage was used in group A,and 100 kV tube voltage was used in group B and C.Personalized injection flow rate of contrast media which determined according to patient's body mass (injection flow rate =λ × body mass) was used for all groups,and the λ values for group A,B and C were 0.07,0.07 and 0.06 ml · kg-1 · s- 1 respectively. CT dose index volume ( CTDIvol ) effective dose(ED) and contrast media dose were evaluated,and these parameters were all analyzed using one-way ANOVA analysis.Image quality of abdominal aorta and branch arteries was rated using a three-point ordinal for all 3 groups,and image quality score was analyzed using Kruskal-Wallis test.Results CTDIvol were (8.2±0.8),(6.0 ±1.0) and (6.1 ±1.1)mGy for group A,B and C,ED were (5.2 ±0.8),(3.5 ± 0.7) and ( 3.6 ± 0.6) mSv,and contrast media dose were (72.3 ± 10.3 ),(73.5 ± 11.3 ) and (61.6 ±9.4) ml,respectively.There were significant differences in CTDlvol,ED and contrast media dose among 3 groups ( F =66.094,77.812,15.919 ; P =0.000).Compare with group A,the ED of group B was decreased 32.7%,and the ED and contrast media dose of group C were decreased 30.8% and 14.8%,respectively.Image quality was rated as excellent,good,and general for 20,19 and 1 patients in group A,25,15 and 0 patients in group B,and 23,17 and 0 patients in group C,respectively.There was no significant difference in image quality score among 3 groups ( x2 =1.492,P =0.474 ).Conclusions The radiation dose and contrast media dose can be decreased in abdominal CTA using low tube voltage and personalized contrast media apolication while image quality can be preserved.

  • [1]孟悛非,范淼.重视CT低剂量研究.中华放射学杂志,2009,43:679-680.
  • [2]张龙江,祁吉.对比剂肾病:一个值得关注的问题.中华放射学杂志,2007,41:882-884.
  • [3]McCollough C,Cody D,Edyvean S,et al.The measurement,reporting,and management of radiation dose in CT.College Park:Tech Rep 96 American Association of Physicists in Medicine,2008:1.
  • [4]Pflederer T,Rudofsky L,Ropers D,et al.Image quality in a low radiation exposure protocol for retrospectively ECG-Gated coronary CT angiography.AJR Am J Roentgenol,2009,192:1045-1050.
  • [5]何新华,胡永胜,王自勇,等.双源CT低管电压技术在超重患者冠状动脉成像中的应用.中华放射学杂志,2011,45:486-491.
  • [6]周旭辉,彭振鹏,郑丽丽,等.64层螺旋CT肺动脉成像低管电压设置结合对比剂个体化应用的对照研究.中华放射学杂志,2009,43:704-707.
  • [7]刘杰,高剑波,郭华.等.腹主动脉CT血管成像的低剂量对比剂应用研究.中华放射学杂志,2011,45:1207-1210.
  • [8]Huda W,Scalzetti EM,Levin G.Technique factors and image quality as functions of patient weight at abdominal CT.Radiology,2000,217:430-435.
  • [9]Nakayama Y,Awai K,Funama Y,et al.Abdominal CT with low tube voltage: preliminary observations about radiation dose,contrast enhancement, image quality, and noise. Radiology,2005.237:945-951.
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