The application of diffusion tensor imaging in cervical spondylosis with 3.0 T MR
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 12
- DOI:
- 10.3760/j.issn:1005-1201.2007.12.005
- Key Word:
- 颈椎病;磁共振成像,弥散
Abstract： 目的 探讨3.0 T MR扩散张量成像(DTI)作为一种定量分析方法在颈椎病中的应用价值.方法 21名健康志愿者(对照组)和84例颈椎病患者行颈髓DTI,根据T2WI表现将颈椎病组分为A(单纯硬膜囊受压)、B(颈髓轻度受压)、C(颈髓受压,T2WI可疑高信号)、D(颈髓受压,T2WI信号增高)4组,每组21例,以健康组为对照,分析颈椎病组表观扩散系数(ADC)、分数各向异性(FA)值及本征(λ1、λ2、λ3)值的变化,对所有受检者行颈髓纤维束成像.结果所有受检者DTI显示满意.21名对照组颈髓平均ADC值为(0.78±0.08)×10-3mm2/s,FA值为0.72±0.03,λ1、λ2、λ3值分别为(1.51±0.15)×10-3mm2/s、(0.42±0.09)×10-3mm2/s、(0.41±0.10)×10-3mm2/s.对照组与硬膜囊受压组比较,ADC(q=1.451)、FA(q=1.999)、λ1(q=1.137)值差异无统计学意义(P值均＞0.05),与λ2(q=3.039)、λ3(q=2.982)值差异存在统计学意义(P值均＜0.05).对照组与B、C、D 3个颈髓受压组比较,ADC值的q值分别为7.982、8.532、14.073,FA值的q值分别为12.206、15.889、26.306,λ1值的q值分别为4.601、4.845、6.631,λ2值的q值分别为6.502、11.060、20.480,λ3值的q值分别为9.782、9.416、16.949,差异均存在统计学意义(P值均＜0.01).结论 ADC、FA、λ1、λ2、λ3值是检测颈髓微结构改变的敏感指标.
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