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Comparison of arterial spin labeling and dynamic susceptibility contrast MRI in patients with acute cerebral ischemia
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 11
- DOI:
- 10.3760/j.issn:1005-1201.2007.11.003
- Key Word:
- 脑缺血;脑血管循环;磁共振成像;灌流
Abstract： 目的 对比研究动脉血质子自旋标记(ASL)与动态磁敏感对比(DSC)MRI在急性脑缺血诊断中的应用价值.方法 27例发病3 d内的急性脑卒中患者,均采用3.0 T MR行脉冲式ASL和DSC MR检查.观察2种技术的灌注表现,包括灌注不足、正常灌注、延迟灌注、过度灌注等,采用Mann-Whitney检验做定性分析.在扩散加权成像显示的病变部位及对侧正常半球的镜像区域分别确定3个感兴趣区(ROI),测量信号强度并计算信号强度比(病侧/对照侧),并将结果 做配对t检验.结果 定性分析显示27例患者中,21例2种技术检查结果 一致(灌注不足14例,正常灌注5例,过度灌注2例).6例2种技术不一致,其中4例ASL显示灌注不足而DSC显示延迟灌注,2例ASL显示正常灌注而DSC显示延迟灌注,两者间差异无统计学意义(P＞0.05).定量分析示,2种技术的病侧与对照侧信号强度比值ASL为0.71±0.46,DSC为0.73±0.42,两者间差异无统计学意义(P＞0.05).结论 无创性ASL技术在检测灌注异常时与DSC MRI有相似的敏感性;ASL可与常规MR检查相结合,为临床诊断急性缺血性卒中提供有价值的信息.
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