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Detection of focal epileptic activity using combined simultaneous electroencephalogram-functional MRI
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 11
- DOI:
- 10.3760/j.issn:1005-1201.2007.11.002
- Key Word:
- 磁共振成像;脑电描记术;癫痫
Abstract： 目的 探讨脑电监测模式的脑电同步功能MR成像(EEG-fMRI)技术在局灶性癫痫患者间期痫样放电引起的脑区激活情况的应用价值.方法 对12例局灶性癫痫患者进行EEG-fMRI数据采集;以间期痫样放电的事件相关设计模式对fMRI数据进行分析,观察癫痫放电引起脑激活的时空分布情况.并与MR结构成像病灶定位结果 进行对比.结果 12例患者中,共采集到10例患者的18次有效EEG-fMRI数据.与结构病灶相对比,11次数据显示定位结果 较好,5次结果 尚可,2次结果 不佳;其中6例患者2次采集的定位结果 相同.18次扫描结果 均显示激活大脑对侧的小脑有稳定的激活;10次结果 中丘脑有正激活信号,9次有位于典型的缺省状态分布脑区的负激活信号.结论 EEG-fMRI技术利用多模态神经成像技术的优点,在癫痫的研究方面有较大的应用价值.
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