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MRI manifestation for the diagnosis of sporadic Creutzfeldt-Jakob disease
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 7
- DOI:
- 10.3760/j.issn:1005-1201.2007.07.004
- Key Word:
- 克-亚二氏综合征;磁共振成像
Abstract： 目的 探讨散发型Creutzfeldt-Jakob病(sCJD)的MR特点.方法 回顾性分析3例临床诊断为sCJD的患者资料,MR采用SE T1WI、快速自旋回波(FSE)T2WI、扩散加权成像(DWI)扫描,观察其MR表现特征.结果 3例SE T1 WI和FSE T2WI序列对基底节区和皮质的病变显示不佳,DWI则可清晰地显示病变,额、顶、枕叶皮质最常受累,表现为高信号,病变可对称,也可不对称,皮层下区脑白质信号未见异常.双侧尾状核、丘脑也可受累,DWI上呈高信号.晚期脑实质广泛萎缩,以皮质为著.结论 sCJD采用DWI序列结合其特征性的临床表现可作出较为准确的诊断.
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