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Evaluation of brain metastases with dynamic susceptibility-contrast MR imaging
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 9
- DOI:
- 10.3760/j.issn:1005-1201.2006.09.002
- Key Word:
- 脑肿瘤;肿瘤转移;磁共振成像;灌注;脑血流
Abstract： 目的 研究治疗前不同来源脑转移瘤的动态增强磁化率(DSC)MR灌注成像特点.方法 对28例经病理或随访证实为脑转移瘤的患者行手术前DSC MR灌注成像扫描.分析MR灌注曲线及伪彩图像,测量肿瘤实质部分及瘤周水肿区最大相对脑血容积(rCBV)值及相应部位相对平均通过时间(rMTT)数值,并将所测量数值进行t检验分析,P＜0.05为差异具有统计意义.结果 不同来源脑转移瘤的MR灌注曲线、伪彩图像特点无明显差异.脑转移瘤肿瘤实质部分灌注程度与正常脑灰质相仿,瘤周水肿区表现为低灌注,两者的灌注时间均延长.12例来源于肺癌与5例来源于乳腺癌的脑转移瘤肿瘤实质部分的最大rCBV值(分别为272.5±34.3和210.8±59.4)及相应部位的rMTT数值(分别为117.7±4.3和105.2±21.3)之间以及两者瘤周水肿区rCBV值(分别为122.0±16.3和68.4±6.1)和rMTT值(分别为112.7±8.3和139.8±37.9)之间差异均无统计学意义(P＞0.05).结论 不同来源脑转移瘤的MR灌注成像特点趋于一致.
- [1]J M, Boorstein,K T, Wong,R I, Grossman,etc.Metastatic lesions of the brain: imaging with magnetization transfer.[J].1994,191.
- [2]W T, Yuh,J D, Engelken,M G, Muhonen,etc.Experience with high-dose gadolinium MR imaging in the evaluation of brain metastases.[J].1900,13.
- [3]D, Barranco,L N, Sutton,S, Florin,etc.Use of 19F NMR spectroscopy for measurement of cerebral blood flow: a comparative study using microspheres.[J].1989,9.
- [4]Sugahara T,Korogi Y,Kochi M,etc.Correlation of MR imaging-determined cerebral blood volume maps with histologic and angiographic determination of vascularity of gliomas.[J].1998.
- [5]V M, Runge,J E, Kirsch,V J, Burke,etc.High-dose gadoteridol in MR imaging of intracranial neoplasms.[J].1900,2.
- [6]H J, Aronen,I E, Gazit,D N, Louis,etc.Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings.[J].1994,191.
- [7]Ricci PE.Imaging of adult brain tumors.[J].1999,9(4).