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Diagnostic value of diffusion-weighted MR imaging in distinguishing low-grade glioma and metastatic tumors
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 10
- DOI:
- 10.3760/j.issn:1005-1201.2005.10.001
- Key Word:
- 磁共振成像;神经胶质瘤;肿瘤转移
Abstract： 目的探讨扩散加权成像(DWI)在高分化胶质瘤与转移瘤中的应用与鉴别价值.方法搜集经临床和手术确诊的16 例胶质瘤(Ⅰ～Ⅱ级)和18 例转移瘤,采用Philips Gyroscan Intera 1.5 T超导MR系统进行常规扫描和DWI.在分析常规图像和DWI图像基础上,进行肿瘤灶(包括肿瘤囊变区、实性组织、瘤周带、瘤周水肿4部分)的表观扩散系数(ADC)值测量,并进行统计学分析.结果16 例胶质瘤主要表现为单发不规则长T1、T2信号,有10 例伴有不同程度的囊性变,12例伴有不同程度瘤周水肿,10例行增强扫描显示病灶强化程度不一,7例呈轻度强化,2例无明显强化,1例中度强化.转移瘤中3例单发,15例多发,DWI可检测(直径均>1.5 cm,可以进行较准确的ADC值测量)的病灶为48个,其中,囊性转移灶5个,囊实性转移灶20个,实性转移灶13个,伴有瘤内出血4例10个病灶.转移瘤主要表现为长T1、T2信号,伴出血时可表现出短T1、T2信号,其中11例增强扫描主要显示为环形或不规则边缘强化.ADC值测量结果显示胶质瘤组较转移瘤组的瘤周带ADC值有明显增高(t=4.455,P<0.01),而两组间在肿瘤实性和囊性组织以及瘤周水肿带的ADC值测量方面差异无统计学意义(P>0.05).结论转移瘤由于生长迅速,可能形成瘤周"致密带",产生相应的压迫效应,从而导致瘤周ADC值较高,此征象可能成为胶质瘤与转移瘤之间的鉴别特点.
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