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Peritumoral brain edema in intracranial tumor evaluated by CT perfusion imaging
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 5
- DOI:
- 10.3760/j.issn:1005-1201.2005.05.004
- Key Word:
- 体层摄影术,X线计算机;脑肿瘤;脑水肿;局部血流
Abstract： 目的应用CT灌注成像半定量估计脑肿瘤瘤周水肿的灌注状况.方法应用Somatom Plus 4螺旋CT机,对21例脑肿瘤瘤周水肿患者[脑膜瘤4例,胶质瘤(Ⅲ～Ⅳ级)7例、转移瘤10例]进行CT灌注成像,经灌注软件处理分别计算瘤周水肿区局部脑血流量(rCBF)、局部脑血容量(rCBV)、对比剂平均通过时间(MTT),并与对侧脑白质和不同肿瘤瘤周水肿间的灌注参数进行比较.结果脑膜瘤和转移瘤瘤周水肿的rCBF和rCBV明显低于对侧脑白质(rCBF:t=2.92和3.82, P值均<0.05,0.005;rCBV:t=2.42和3.53, P<0.05,0.01),胶质瘤瘤周水肿的rCBF和rCBV与正常脑白质无明显差别(t=1.00和1.33, P值均>0.05).瘤周水肿区与对侧正常脑白质rCBF、rCBV比值,脑膜瘤和转移瘤之间差异无统计学意义(t=0.23和0.73, P值均>0.05),胶质瘤明显大于脑膜瘤和转移瘤(t=3.05和3.37, P<0.01,0.005).结论脑膜瘤和转移瘤瘤周水肿区的rCBF、rCBV显著降低,而胶质瘤瘤周水肿区接近或高于对侧脑白质,CT灌注能定量脑肿瘤瘤周水肿血流灌注状况,有助于肿瘤的鉴别和随访.
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