Preliminary research on multi-slice helical CT perfusion and MR perfusion in soft tissue tumors
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 11
- DOI:
- 10.3760/j.issn:1005-1201.2004.11.004
- Key Word:
- 软组织肿瘤;体层摄影术,X线计算机;磁共振成像;病理学;对比研究
Abstract： 目的 探讨多层螺旋CT(MSCT)及MR灌注成像对软组织肿瘤的良恶性鉴别诊断价值.方法 分别对软组织肿瘤26例(良性15例,恶性11例)行MSCT灌注成像、29例(良性17例,恶性12例)行MR灌注成像,通过灌注软件分析灌注参数在良恶性肿瘤中的差异.结果 MSCT灌注成像结果:恶性组血流速度(BF)为(24.49±14.49)ml·100 mg(-1·min-1,良性组BF为(1.98±1.19)ml·100 mg-1·min-1;表面通透性(PS) 恶性组为(14.64±1.89)ml·100 mg-1·min-1,良性组为(2.40±0.38)ml·100 mg-1·min-1.良恶性软组织肿瘤间的BF、PS值差异具有显著性意义(P值均<0.05);血容量(BV)、平均通过时间(MTT)值差异则无显著性意义(P值均>0.05).MSCT灌注成像诊断软组织恶性肿瘤的灵敏度为90.910/11),特异度为86.7%(13/15),准确度为88.5%(23/26),阳性预测值为83.3%(10/12),阴性预测值为92.9%(13/14).MR灌注成像结果:恶性组BF为(0.11±0.02)ml·100mg-1·min-1 ,良性组为(0.07±0.01)ml·100 mg-1·min-1;良、恶性软组织肿瘤之间的BF值差异具有显著性意义(P<0.05);BV、MTT值差异则无显著性意义(P>0.05).MR灌注成像诊断恶性肿瘤的灵敏度为91.7%(11/12),特异度为88.2%(15/17),准确度为89.7%(26/29),阳性预测值为84.6%(11/13),阴性预测值为93.8%(15/16).结论 MSCT及MR灌注成像有助于软组织肿瘤的良恶性鉴别.
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